氫氣分子醫學文獻匯總（自2011年全文並持續更新）
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11. Cai JM, Kang ZM, Liu W, et al. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci lett 2008,441(2):167-72 pdf
12. Hayashida K, Sano M, Ohsawa I, et al. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun, 2008,373(1):30-5.pdf
13. Kajiyama S, Hasegawa G, Asano M, et al. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance, Nutr. Res, 2008,28:137-43 pdf
14. Ohsawa I, Nishimaki K, Yamagata K, et al. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.Biochem Biophys Res Commun, 2008, 377(4):1195-8 pdf
15. Sato Y, Kajiyama S, Amano A, et al. Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice. Biochem Biophys Res Commun, 2008; 375(3):346-50. pdf
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21. Cai JM, Kang ZM, Liu K, et al. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Res. 2009;1256:129-37.pdf
22. Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S.Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.Cancer Chemother Pharmacol. 2009; 64(4):753-61. pdf
23. Zheng XF, Mao YF, Cai JM, Li YH, Liu WW, Sun PL, Zhang JH, Sun XJ, Yuan.HB Hydrogen-Rich Saline Protects against Intestinal Ischemia/Reperfusion Injury in Rats Free Radical Res.2009; 43(5):478-84. pdf
24. Fu Y, Ito M, Fujita Y, et al. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson’s disease. Neurosci lett. 2009; 453(2):81-5. pdf
25. Matchett GA, Fathali N, Hasegawa Y, et al. Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models.Brain Res. 2009; 1259:90-7. pdf
26. Mao YF, Zheng XF, Cai JM, et al. Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. Biochem Biophys Res Commun.2009; 381(4):602-5. pdf
27. Akito Shimouchi, Kazutoshi Nose, Makoto Yamaguchi, Hiroshi Ishiguro Takaharu Kondo. Breath Hydrogen Produced by Ingestion of Commercial Hydrogen Water and Milk.Biomarker Insights 2009:4 27-32. pdf
28. Kikkawa YS, Nakagawa T, Horie RT, Ito J.Hydrogen protects auditory hair cells from free radicals.Neuroreport. 2009;20(7):689-94. pdf
29. Suzuki Y, Sano M, Hayashida K, Ohsawa I, Ohta S, Fukuda K. Are the effects of α-glucosidase inhibitors on cardiovascular events related to elevated levels of hydrogen gas in the gastrointestinal tract? FEBS Lett. 2009; 583(13):2157-9. pdf
30. Kajiya M, Sato K, Silva MJ, Ouhara K, Do PM, Shanmugam KT, Kawai T. Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis. Biochem Biophys Res Commun. 2009; 386(2):316-21. pdf
31. Kajiya M, Silva MJ, Sato K, Ouhara K, Kawai T. Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. Biochem Biophys Res Commun. 2009 Aug 14;386(1):11-5. 2009; 386(1):11-5. pdf
32. Sun Q, Kang ZM, Cai JM, Liu WW, Liu Y. Zhang JH, Denoblec PJ, Tao HY, Sun XJ.Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats Exp Biol Med.2009; in press pdf
33. Chen H, Sun YP, Hu PF, Liu WW, Xiang HG, Li Y,Yan RL, Su N, Ruan CP, Sun XJ, Wang Q.The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats. J Surg Res.2009; in press pdf
34. Milton SL.HYDROGEN SALINE A REAL GAS. J Exp Biol. 2009 in press pdf comment to our paper
35. Shimouchi A, Nose K, Takaoka M, Hayashi H, Kondo T.Effect of dietary turmeric on breath hydrogen. Dig Dis Sci. 2009 Aug;54(8):1725-9. Epub 2008 Nov 26 pdf
36. Xu J, Zhou JR, Cai JM, Zhu Z, Sun XJ, Jiang CL.Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema. Inflammation Res.2009 in press pdf
37. Itoh T, et al. Molecular hydrogen suppresses FcεRI-mediated signal transduction and preventsdegranulation of mast cells. Biochem Biophys Res Commun. 2009. in press pdf
38. Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, et al. Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson’s Disease. PLoS ONE. 2009; 4(9): e7247. doi:10.1371/journal.pone.0007247 pdf
39. Y. Saitoh, Y. Yoshimura, K. Nakano, N. Miwa. Platinum nanocolloid-supplemented hydrogendissolved water inhibits growth of human tongue carcinoma cells preferentially over normal cells.Experimental Oncology 31, 156–162, 2009 pdf
40. Nakao, A, Kaczorowski, D J, Wang, Y, Cardinal, J S, Buchholz, B M, Sugimoto, R, Tobita, K, Lee, S, Toyoda, Y, Billiar, T R, McCurry, K R. Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. J Heart Lung Transplant. 2010 May;29(5):544-53. Epub 2009 Dec 24. pdf
41. Xie K, Yu Y, Pei Y, Hou L, Chen S, Xiong L, Wang G.. Protective Effects of Hydrogen Gas on Murine Polymicrobial Sepsis via Reducing Oxidative Stress and HMGB1 Release. Shock. 2010 Jul;34(1):90-7. pdf
42. Oharazawa H et al.Rapid Diffusion of Hydrogen Protects the Retina: Administration to the Eye of Hydrogen-Containing Saline in Retinal Ischemia-Reperfusion Injury. Investigative Ophthalmology & Visual Science 2010;51:487-492 pdf
43. Qian L, Cao F, Cui J, Huang Y, Zhou X, Liu S, Cai J. Radioprotective effect of hydrogen in cultured cells and mice. Free Radical Res. 2010;44:275-82 pdf
44. Cardinal JS, Zhan J, Wang Y, Sugimoto R, Tsung A, McCurry KR, Billiar TR, Nakao A.Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney Int. 2010;77(2):101-9. pdf
45. George JF, Agarwal A.Hydrogen: another gas with therapeutic potential. Kidney Int. 2010 Jan;77(2):85-7. pdf
46. Liu C, Cui JG, Sun Q, Cai JM. Hydrogen therapy may be an effective and specific novel treatment for acute radiation syndrome. Medical Hypotheses.2010;74:145-146 pdf
47. Chen H, Sun YP, Li Y, Liu WW, Xiang HG, Fan LY, Sun Q, Sun XJ, Wang Q. Hydrogen-rich saline ameliorates the severity of L-arginine-induced acute pancreatitis in rats. Biochem Biophys Res Commun.2010; 393:308-13 pdf
48. LI J, WANG C, Zhang JH, CAI JM, CAO YP, SUN XJ. Hydrogen-rich Saline Improves Memory Function in a Rat Model of Amyloid-beta-induced Alzheimer’s Disease by Reduction of Oxidative Stress.Brain res.2010; pdf
49. Shen MH, Cai JM, Sun Q, He J, Sun XJ, Huo ZL. Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning. Medical Hypotheses.2010 pdf in press
50. Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N.Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr. 2010 Mar;46(2):140-9. Epub 2010 Feb 24. pdf [Abstract] [PDF (250K)]
51. Saitoh Y, Harata Y, Mizuhashi F, Nakajima M, Miwa N. Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. Toxicol Ind Health. 2010 Mar 4. [Epub ahead of print] pdf
52. Chen CW, Chen QB, Mao YF, Xu SM, Xia CY, Shi XY, Zhang JH, Yuan HB, Sun XJ. Hydrogen-rich saline protects against spinal cord injury in rats.Neurochem Res. 2010;in press pdf
53. Liu Q, Shen WF, Sun HY, Fan DF, Nakao A, Cai JM, Yan G, Zhou WP, Shen RX, Yang JM, Sun XJ. Hydrogen-Rich Saline Protects against Liver Injury in Rats with Obstructive Jaundice.Liver International 2010 pdf
54. Xie K, Yu Y, Zhang Z, Liu W, Pei Y, Xiong L, Hou L, Wang G. HYDROGEN GAS IMPROVES SURVIVAL RATE AND ORGAN DAMAGE IN ZYMOSAN-INDUCED GENERALIZED INFLAMMATION MODEL. Shock. 2010 Mar 23. pdf
55. C.H. Chen, M. Anatol, Y. Zhan, W.W. Liu, R.P. Ostrowki, J. Tang, J.H. Zhang. Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model Neuroscience. 2010; In Press, pdf
56. Nakayama M, Nakano H, Hamada H, Itami N, Nakazawa R, Ito S. A novel bioactive haemodialysis system using dissolved dihydrogen (H2) produced by water electrolysis: a clinical trial. Nephrol Dial Transplant. 2010 Apr 12. pdf
57. Zheng J, Liu K, Kang Z, Cai J, Liu W, Xu W, Li R, Tao H, Zhang JH, Sun X. Saturated hydrogen saline protects lung against oxygen toxicity. Undersea Hyperb Med. 2010;37(3):185-92. pdf
58. Shingu C, Koga H, Hagiwara S, Matsumoto S, Goto K, Yokoi I, Noguchi T. Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury. J Anesth. 2010 May 18. [Epub ahead of print] PDF
59. Gu Y, Huang CS, Inoue T, Yamashita T, Ishida T, Kang KM, Nakao A. Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. J Clin Biochem Nutr. 2010 May;46(3):269-76. Epub 2010 Apr 23. pdf web
60. Kitamura A, Kobayashi S, Matsushita T, Fujinawa H, Murase K. Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced CT. Br J Radiol. 2010 Jun;83(990):509-14.pdf
61. Haruhisa Kawasaki, Jianjun Guan, Kenichi Tamama. Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials Biochemical and Biophysical Research Communications, 2010 pdf
62. Chen QB et al. Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress and BDNF in spinal cord in a chronic constriction injury rat model. Brain res.2010; 35(7):1111-8 pdf. pdf
63. Huang et al. Hydrogen Gas Inhalation Attenuates Ventilator-Induced Lung Injury In Mice. Am. J. Respir. Crit. Care Med..2010; 181: A3751 ms
64. Ji X, Liu W, Xie K, Liu W, Qu Y, Chao X, Chen T, Zhou J, Fei Z.Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress. Brain res. 2010 pdfl
65. Ueda Y, Nakajima A, Oikawa T. Hydrogen-Related Enhancement of In Vivo Antioxidant Ability in the Brain of Rats Fed Coral Calcium Hydride. Neurochem Res. 2010 Jul 22. pdf
65. Domoki F, Oláh O, Zimmermann A, Németh I, et al. Hydrogen is neuroprotective and preserves cerebrovascular reactivity in asphyxiated newborn pigs. Pediatric Research. 2010. pdf
66. Liu SL, Tao HY, Sun Q, Sun XJ. Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injury. Medical Hypotheses. 2010; in press pdf pdf
67. Qian LR, li BL, Cao F, Huang YC, Liu SL, Cai JM, Gao F. HYDROGEN-RICH PBS PROTECTS CULTURED HUMAN CELLS FROM IONIZING RADIATION-INDUCED CELLULAR DAMAGE. Nuclear Technology &Radiation Protection.2010 pdf
68. Zhang YF, Sun Q, He B, Xiao J, Wang ZN, Sun XJ. Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. International Journal of Cardiology.2010; pdf
69. Huang CS, Kawamura T, Toyoda Y, Nakao A.Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res. 2010 Sep;44(9):971-82. pdf review
70. Schoenfeld MP, Ansari RR, Zakrajsek JF, Billiar TR, Toyoda Y, Wink DA, Nakao A Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.Medical Hypotheses. 2010; pdf in press
71. Sun Q, Cai JM, Liu SL, Liu Y, Xu WG, Tao HY, Sun XJ. Hydrogen-rich saline provides protection against hyperoxic lung injury. J Surg Res. 2011;165:e43–e49 pdf offprint
72. Kubota M, Shimmura S, Kubota S, Miyashita H, Kato N, Noda K, Ozawa Y, Usui T, Ishida S, Umezawa K, Kurihara T, Tsubota K. Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model. Invest Ophthalmol Vis Sci. 2010 Sep 16. pdf
73. Chen X, et al. Lactulose: an indirect antioxidant ameliorating inflammatory bowel disease by increasing hydrogen production. Medical Hypotheses 2010 pdf1
74. Sun H, Chen L, Zhou W, Hu L, Li L, Tu Q, Chang Y, Liu Q, Sun X, Wu M, Wang H.The Protective Role of Hydrogen -Rich Saline in Experimental Liver Injury in Mice. j hepatology. 2010; pdf
75. Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, Yamasoba T. Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs. Neurosci Lett. 2010; pdf
76. Sun Q, Cai JM,Zhou JR,Tao HY,Zhang JH,Zhang W,Sun XJ.Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. Critical Care Medicine. 2010 in press
77. Wang F, Yu G, Liu SY, Li JB, Wang JF, Bo LL, Sun XJ, Deng XM.Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats. J Surg Res.2010; in press
78. Kawamura T, Huang CS, Tochigi N, Lee S, Shigemura N, Billiar TR, Okumura M, Nakao A, Toyoda Y.Inhaled Hydrogen Gas Therapy for Prevention of Lung Transplant-Induced Ischemia/Reperfusion Injury in Rats. Transplantation. 2010 Nov 2. [Epub ahead of print] pdf
79. Li Y, Hamasaki T, Nakamichi N, Kashiwagi T, Komatsu T, Ye J, Teruya K, Abe M, Yan H, Kinjo T, Kabayama S, Kawamura M, Shirahata S.Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. Cytotechnology. 2010 Nov 10. [Epub ahead of print] pdf
80. Yan H, Tian H, Kinjo T, Hamasaki T, Tomimatsu K, Nakamichi N, Teruya K, Kabayama S, Shirahata S. Extension of the lifespan of Caenorhabditis elegans by the use of electrolyzed reduced water. Biosci Biotechnol Biochem. 2010 Oct 23;74(10):2011-5. pdf
81. Fang Y. Fu XJ, Gu C, Xu P, Wang Y, Yu WR, Sun Q, Sun XJ, Yao M. Hydrogen-Rich Saline Protects against Acute Lung Injury Induced by Extensive Burn in Rat Model. J Burn Care Res.
82. Qian L, Cao F, Cui J, Wang Y, Huang Y, Chuai Y, Zaho L, Jiang H, Cai J.The potential cardioprotective effects of hydrogen in irradiated mice. J Radiat Res (Tokyo). 2010;51(6):741-7 pdf
83. Huang Y, Xie KL, Li JP, Xu N, Gong G, Wang GL, Yu YH, Dong HL, Xiong LZ. Beneficial Effects of Hydrogen Gas against Spinal Cord Ischemia-Reperfusion Injury in Rabbits. Brain res. 2011; in press
84. Qian LR, Li BL, Cai JM, Gao F. The Hypothesis of an Effective Safe and Novel Radioprotective Agent Hydrogen-rich Solution West Indian Med J. 2010; 59 (2): 122-4
85. Taura A, Kikkawa YS, Nakagawa T, Ito J. Hydrogen protects vestibular hair cells from free radicals. Acta Otolaryngol Suppl. 2010;563:95-100. pdf
86. Zhu WJ et al. Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats. Nephrol. Dial. Transplant. (2010) doi: 10.1093/ndt/gfq727 pdf
87. Liu SL, Liu K, Sun Q, Liu WW, Xu WG, Denoble P, Tao HY, Sun XJ. Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. J Biomed Biotechnol. 2011;
88. Hong Y, Chen S, Zhang JM. Hydrogen as a Selective Antioxidant: a Review of Clinical and Experimental Studies.J Int Med Res. 2010; 38: 1893-1903 pdf
以上文章全文请到这个地址下载 http://www.sciencenet.cn/m/user_content.aspx?id=247619
89 Wang C, Li J, Liu Q, Yang R, Zhang JH, Cao YP, Sun XJ. Hydrogen-rich Saline Reduces Oxidative Stress and Inflammation by Inhibit of JNK and NF-κB Activation in a Rat Model of Amyloid-beta-induced Alzheimer's Disease. Neurosci Lett. 2011 Jan 13. [Epub ahead of print]
90 Zheng XF, Sun XJ, Xia ZF Hydrogen Resuscitation, a New Cytoprotective Approach. Clin Exp Pharmacol Physiol.2011; http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1681.2011.05479.x/abstract
91 Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice. Obesity (Silver Spring). 2011 Feb 3. [Epub ahead of print]
92 Wang Y, Jing L, Zhao XM, Han JJ, Xia ZL, Qin SC, Wu YP, Sun XJ.Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. Respir Res. 2011 Mar 4;12:26.pdf
93 Ji Q, Hui K, Zhang L, Sun X, Li W, Duan M.The Effect of Hydrogen-Rich Saline on the Brain of Rats with Transient Ischemia. J Surg Res. 2011 Mar 2. [Epub ahead of print]pdf
94 Shen L, Wang J, Liu K, Wang CZ, Wang CT, Wu HW, Sun Q, Sun XJ, Jing H.Hydrogen-Rich Saline is Cerebroprotective in a Rat Model of Deep Hypothermic Circulatory Arrest. Neurochem Res DOI 10.1007/s11064-011-0476-4pdf
95. Chuai Y, Zhao L, Ni J, Sun D, Cui J, Li B, Qian L, Gao F, Cai J. A possible prevention strategy of radiation pneumonitis: Combine radiotherapy with aerosol inhalation of hydrogen-rich solution. Med Sci Monit. 2011 Apr 1;17(4):HY1-4.
96. Song G, Tian H, Liu J, Zhang H, Sun X, Qin S. H(2) inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells. Biotechnol Lett. 2011 May 5. [Epub ahead of print]
97. Pan Yu, Zhenxiang Wang, Xuejun Sun, Xiaohua Chen, Suyun Zeng, Liang Chen, Shirong Li. Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage. Biochemical and Biophysical Research Communications, 2011
98. Huang CS, Kawamura T, Peng X, Tochigi N, Shigemura N, Billiar TR, Nakao A, Toyoda Y. Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation. Biochemical and Biophysical Research Communications, 2011;408(2):253-8. Epub 2011 Apr 5.
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